Understanding SARS-CoV-2-Mediated Inflammatory Responses: From
Por um escritor misterioso
Descrição
Currently there is no effective antiviral therapy for SARS-CoV-2 infection, which frequently leads to fatal inflammatory responses and acute lung injury. Here, we discuss the various mechanisms of SARS-CoV-mediated inflammation. We also assume that SARS-CoV-2 likely shares similar inflammatory responses. Potential therapeutic tools to reduce SARS-CoV-2-induced inflammatory responses include various methods to block FcR activation. In the absence of a proven clinical FcR blocker, the use of intravenous immunoglobulin to block FcR activation may be a viable option for the urgent treatment of pulmonary inflammation to prevent severe lung injury. Such treatment may also be combined with systemic anti-inflammatory drugs or corticosteroids. However, these strategies, as proposed here, remain to be clinically tested for effectiveness.
Blocking Immune System Pathway May Stop COVID-19 Infection, Prevent Severe Organ Damage
Cell‐mediated immunity to SARS‐CoV‐2 - Wang - 2020 - Pediatric Investigation - Wiley Online Library
Inflammatory pathways in COVID‐19: Mechanism and therapeutic interventions - Jiang - 2022 - MedComm - Wiley Online Library
FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age
Inflammatory Response Leads to Neuronal Death in Human Post-Mortem Cerebral Cortex in Patients with COVID-19
Experimental Model of Pulmonary Inflammation Induced by SARS-CoV-2 Spike Protein and Endotoxin
Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19
Involvement of autophagy in lymphocyte-mediated inflammation during
COVID-19 - Wikipedia
Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2
COVID-19: Coronavirus replication, pathogenesis, and therapeutic strategies
Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome
Most Cited Virologica Sinica Articles
de
por adulto (o preço varia de acordo com o tamanho do grupo)
